tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate

tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate - Names and Identifiers

Name	tert-Butyl [(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate
Synonyms	tert-Butyl ((2S,3R)-3-hydroxy-4-(N-isobutyl-4-nitro-phenylsulfonamido)-1-phenylbutan-2-yl)carb tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate tert-Butyl (2S,3R)-3-hydroxy-4-(N-isobutyl-4-nitrophenylsulfonamido)-1-phenylbutan-2-ylcarbamate tert-Butyl ((2S,3R)-3-hydroxy-4-(N-isobutyl-4-nitro-phenylsulfonamido)-1-phenylbutan-2-yl)carbama tert-Butyl [(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate tert-butyl [(2S,3R)-3-hydroxy-4-{(2-methylpropyl)[(4-nitrophenyl)sulfonyl]amino}-1-phenylbutan-2-yl]carbamate [(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl[(4-nitro-phenyl)sulfonyl)]amino]propyl]-carbamic Acid tert-Butyl Ester N-[(1S,2R)-2-Hydroxy-3-[(2-methylpropyl)[(4-nitrophenyl)sulfonyl]amino]-1-(phenylmethyl)propyl]-carbamic Acid 1,1-Dimethylethyl Ester CarbaMic acid,N-[(1S,2R)-2-hydroxy-3-[(2-Methylpropyl)[(4-nitrophenyl)sulfonyl]aMino]-1-(phenylMethyl)propyl]-,1,1-diMethylethyl ester
CAS	191226-98-9
InChI	InChI=1/C25H35N3O7S/c1-18(2)16-27(36(33,34)21-13-11-20(12-14-21)28(31)32)17-23(29)22(15-19-9-7-6-8-10-19)26-24(30)35-25(3,4)5/h6-14,18,22-23,29H,15-17H2,1-5H3,(H,26,30)/t22-,23+/m0/s1

tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate - Physico-chemical Properties

Molecular Formula	C25H35N3O7S
Molar Mass	521.63
Density	1.241
Melting Point	166-168 ºC
Solubility	Acetone, Chloroform, Dichloromethane, Ethyl Acetate
Appearance	Solid
Color	White
pKa	11.94±0.46(Predicted)
Storage Condition	Refrigerator
Refractive Index	1.568

tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate - Introduction

(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl [(4-nitrophenyl)sulfonyl] amino] propyl] carbamic acid tert-butyl ester, also known as (1S,2R)-tert-Butyl N-[(4-nitrophenyl)sulfonyl]-(S)-3-(benzyloxy)-is an organic compound. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: White solid
-Molecular formula: C26H32N4O7S
-Molecular weight: 528.62g/mol
-Melting point: 128-130 ° C
-Solubility: Soluble in ethanol and chloroform, insoluble in water

Use:
The compound is commonly used in pharmaceutical synthesis and organic chemical reactions, as a catalyst, intermediate or reaction protecting group. It has symmetry and chiral structure, which is suitable for the synthesis of chiral drugs, especially in the synthesis of chiral acids.

Method:
(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl [(4-nitrophenyl)) the preparation method of sulfonyl] amino] propyl] carbamic acid tert-butyl ester is as follows:
1. React (1S,2R)-tert-Butyl N-[(4-nitrophenyl)sulfonyl]-(R)-with benzyl bromide in the presence of base.
2. The product is subjected to alkaline hydrolysis.
3. The final formic acid esterification reaction.

Safety Information:
No (1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl [(4-nitrophenyl) detailed safety information report for tert-butyl sulfonyl] amino] propyl] carbamate. In view of the structural characteristics of this compound, Please strictly observe the laboratory safety practice when using it, and please refer to the relevant safety data sheet. Consult suppliers or experts at specialized chemical laboratories if required.

Last Update：2024-04-09 02:00:43

tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate

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CAS: 191226-98-9
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tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate

tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate

tert-Butyl [(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate

CAS: 191226-98-9

Molecular Formula: C25H35N3O7S

tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate - Names and Identifiers

tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate - Physico-chemical Properties

tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate - Introduction

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tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate Request for Quotation

tert-Butyl [(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate

CAS: 191226-98-9

Molecular Formula: C25H35N3O7S

tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate - Names and Identifiers

tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate - Physico-chemical Properties

tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate - Introduction

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tert-Butyl[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate